| W | M | 35 | 01/06/2022 | A) Fentanyl Intoxication II) Covid-19 | WCSP (New Lenox Twp) | Accident |
| BW | M | 22 | 01/07/2022 | a) Fentanyl Intoxication | Joliet | Accident |
| B | M | 38 | 01/09/2022 | a) Cocaine, Fentanyl, and Alcohol Intoxication | Joliet | Accident |
| W | F | 41 | 01/11/2022 | a) Fentanyl Intoxication | Bolingbrook | Accident |
| W | F | 19 | 01/05/2022 | a) Fentanyl Intoxication | Joliet | Accident |
| B | M | 28 | 01/14/2022 | a) Alcohol, Cocaine, and Fentanyl Intoxication | Joliet | Accident |
| W | M | 51 | 01/28/2022 | a) Fentanyl Intoxication | Romeoville | Accident |
| W | F | 30 | 01/21/2022 | a) Fentanyl, 7-Amino Clonazepam, and Alcohol Intoxication | Joliet | Accident |
| B | M | 54 | 01/30/2022 | a) Fentanyl, Cocaine, Alcohol, and Xylazine intoxication | Joliet | Accident |
| B | M | 62 | 01/09/2022 | a) Fentanyl, Heroin, Cocaine, and Alcohol Intoxication II) Coronary Atherosclerosis | WCSP (Lockport Twsp) | Accident |
| H | M | 25 | 01/31/2022 | a) Fentanyl Intoxication | Joliet | Accident |
| H | M | 45 | 01/21/2022 | a) Fentanyl and Para-Fluorofentanyl Toxicity | Joliet | Accident |
| W | M | 31 | 02/09/2022 | a) Mitragynine, Fentanyl, and Cocaine Intoxication | New Lenox | Accident |
| W | M | 34 | 02/16/2022 | a) Fentanyl and Xylazine Intoxication | Shorewood | Accident |
| B | F | 35 | 02/23/2022 | a) Cocaine and Fentanyl Intoxication | Crest Hill | Accident |
| W | M | 28 | 01/31/2022 | a) Fentanyl and Heroin Intoxication | Wilmington | Accident |
| W | M | 39 | 02/15/2022 | A) Fentanyl and Heroin Intoxication | Joliet | Accident |
| W | F | 51 | 02/16/2022 | a) Fentanyl and Hydrocodone Intoxication | Joliet | Accident |
| W | F | 51 | 02/18/2022 | a) Cocaine, Methamphetamine, and Fentanyl Intoxication | Joliet | Accident |
| W | F | 28 | 03/09/2022 | a) Fentanyl and Cocaine Intoxication | Joliet | Accident |
| W | M | 24 | 03/10/2022 | a) Fentanyl and Cocaine Intoxication | Bolingbrook | Accident |
| W | M | 55 | 02/22/2022 | a) Fentanyl Intoxication | Romeoville | Accident |
| W | M | 29 | 02/25/2022 | a) Fentanyl Intoxication | Elwood | Accident |
| W | M | 54 | 02/19/2022 | a) Fentanyl Intoxication | Braidwood | Accident |
| W | M | 57 | 03/29/2022 | a) Fentanyl and Cocaine Intoxication | WCSP (Homer Twp) | Accident |
| B | M | 29 | 04/03/2022 | a) Fentanyl and Cocaine Intoxication | WCSP (Crete Twp) | Accident |
| B | F | 56 | 04/03/2022 | a) Fentanyl and Cocaine Intoxication | WCSP (Crete Twp) | Accident |
| W | M | 34 | 03/14/2022 | a) Fentanyl, Acetyl Fentanyl and Heroin Intoxication | Naperville | Accident |
| H | M | 32 | 04/04/2022 | a) Fentanyl and Alcohol Intoxication II) Dilated Cardiomyopathy and Obesity | Joliet | Accident |
| W | F | 22 | 04/14/2022 | a) Fentanyl Intoxication | WCSP (Joliet Twp) | Accident |
| W | M | 48 | 03/24/2022 | a) Heroin and Fentanyl Intoxication | WCSP (Crete Twp) | Accident |
| B | M | 39 | 03/26/2022 | a) Fentanyl, Cocaine, Heroin and Alcohol Intoxication | Crest Hill | Accident |
| H | M | 23 | 04/14/2022 | a) Fentanyl and Cocaine Intoxication | WCSP (Joliet Twp) | Accident |
| W | M | 44 | 04/09/2022 | a) Fentanyl, Cocaine and Heroin Intoxication | WCSP (Lockport Twp) | Accident |
| B | M | 29 | 04/23/2022 | a) Fentanyl, Cocaine and Alcohol Intoxication | Crest Hill | Accident |
| W | F | 34 | 01/30/2022 | a) Fentanyl Intoxication | Joliet | Accident |
| A | M | 38 | 04/03/2022 | a) Fentanyl and Cocaine Intoxication | Bolingbrook | Accident |
| W | M | 46 | 04/08/2022 | a) Fentanyl and Cocaine Intoxication | Joliet | Accident |
| H | M | 23 | 04/14/2022 | a) Anoxic Encephalopathy b) Para-Fluorofentanyl and Alcohol Intoxication | Joliet | Accident |
| W | F | 43 | 05/02/2022 | a) Fentanyl, Cocaine and Methamphetamine Intoxication | Joliet | Accident |
| H | M | 30 | 04/13/2022 | a) Fentanyl and Cocaine Intoxication | Romeoville | Accident |
| H | M | 38 | 05/08/2022 | a) Fentanyl and Cocaine Intoxication | Lockport | Accident |
| W | F | 40 | 05/10/2022 | a) Acetyl Fentanyl, Cocaine, and Fentanyl Intoxication | Romeoville | Accident |
| H | F | 26 | 05/12/2022 | a) Fentanyl and Cocaine Intoxication | Joliet | Accident |
| W | M | 28 | 04/30/2022 | A) Fentanyl, Polysubstance, and Thiosulfate/Hydrogen Sulfide Intoxication | Frankfort | Suicide |
| W | F | 36 | 05/19/2022 | A) Fentanyl and Methamphetamine Intoxication | WCSP (Custer Twp) | Accident |
| W | M | 36 | 05/20/2022 | A) Cocaine, Morphine, and Fentanyl Intoxication | Joliet | Accident |
| W | F | 59 | 05/21/2022 | A) Fentanyl and Cocaine Intoxication II) Fatty Liver | Lockport | Accident |
| W | F | 47 | 05/22/2022 | a) Fentanyl and Cocaine Intoxication | Joliet | Accident |
| B | M | 55 | 05/25/2022 | a) Fentanyl, Cocaine, and Alcohol Intoxication | WCSP ( Joliet Twp) | Accident |